The origin of the production of diphtheria antitoxin in France, between philanthropy and commerce.

Evolution in the Production and control of Equine Tetanus Antitoxin During the last 3 decades in Iran.

Is Second Attack of Diphtheria Possible?

' One attack of diphtheria does not always confer a lasting immunity, second and even third attacks are not uncommon. This is probably because our body cells respond slowly to stimulation by diphtheria toxin with the production of antitoxin and the ordinary attack of diphtheria is too brief in duration for adequate stimulation of antitoxin production. This is indicated by the fact that several ...

Impact of vaccination on epidemiology of diphtheria and pertussis

Whooping cough and diphtheria are vaccine preventable diseases. Diphtheria, due to Corynebacterium diphtheriae or Corynebactium ulcerans, two Gram positive bacteria, is a serious upper respiratory tract disease with high morbidity and mortality rates. Vaccination, via an acellular vaccine composed only of purified, detoxified diphtheria toxin, has significantly reduced the incidence of the dise...

Mystical Theory of Ethics

Ethics and mysticism are two transcendental desires of human. Therefore, deliberation on the proportion of mysticism and ethics is important for scholars of the both fields. Some scholars, however, have considered mysticism as incompatible with ethics and some others as something beyond it. Mystics` hermit and their state of being in full meditation and introspection have caused some scholars t...

Design and Production of Recombinant TAT Protein Structure, Catalytic Domain of Diphtheria Toxin, and Evaluation of Its Effect on Cell Line

Background and Objectives: Cancer is one of the most deadly diseases in the present age and its conventional therapies have had low success. Toxin therapy of cancer is a new therapeutic approach, which has attracted the attention of pharmaceutical specialists. Diphtheria toxin consists of three functional, transducing, and binding domains, that the functional part inhibits protein synthesis and...